Bedaquiline Solid

Bedaquiline SolidBedaquiline, a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000).

commonly found in soil

JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than CDK3/4/6 in cell-free assays

a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation

feature Dual Core 2 x 1 GHz processor which delivers noticeable performance improvements including faster operation and shorter stabilization time retaining high repeatability values

anticancer

The brand new adjustment system guarantees the highest measurement accuracy

PD184352 (CI-1040) is an ATP non-competitive MEK1/2 inhibitor with IC50 of 17 nM in cell-based assays

The narrow profile uses less space on shelves

DHFR and GARFT with Ki of 1

PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays

decreasing low-density lipoprotein cholesterol and triglycerides

4-Hydroxy-3