GSK1070916 Non-treat

GSK1070916 Non-treatGSK1070916 is a reversible and ATP competitive inhibitor of Aurora B C with IC50 of 3. 5 nM 6. 5 nM. It displays >100 fold selectivity against the closely related Aurora A TPX2 complex. Phase 1.

Corning Costar 75mm Transwell with 0

MW : 148 kD

Dihydromyricetin (Ampelopsin

used to lower cholesterol

Ibuprofen Lysine is a non-steroidal anti-inflammatory drug

fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 1

PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay

TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM

-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis

a histamine congener

Glycyrrhizin (Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress

It also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1